انفورماتیک در زیست شناسی، بهداشت و غذا

انفورماتیک در زیست شناسی، بهداشت و غذا

Radiographic and Clinical Outcomes of OsvehOss Synthetic Bone Grafts in Spinal Degenerative Diseases, 12-Months Follow-up

نوع مقاله : مقاله پژوهشی

نویسندگان
1 Osveh Asia Medical Instrument Co., Mashhad, Iran.
2 Osveh Asia Medical Instrument Co., Mashhad, Iran Mashhad, Iran
3 Department of Neurosurgery, Farabi Hospital, Mashhad, Iran. Mashhad, Iran
4 Department of Neurosurgery, Farabi Hospital, Mashhad, Iran Mashhad, Iran
5 Materials Research Group, Academic Center for Education, Culture & Research (ACECR), Mashhad branch, Azadi square, Mashhad, Iran.
6 Materials Research Group, Academic Center for Education, Culture & Research (ACECR), Mashhad branch, Mashhad, Iran.
7 Faculty Member of Mashhad Branch of Islamic Azad University
چکیده
The emergence of synthetic bone graft substitutes as a viable option for treatment of a range of bony defects has revolutionized the field of tissue engineering. The iliac crest bone grafting (ICBG) technique for lumbar posterolateral fusion surgery is widely used; however, donor site problems such as pain and sensory disturbance have been reported. Local bone is available for fusion surgery, but its reliability as a graft has not been fully reported and documented. In addition, there has been a focus on finding suitable substitutes for autogenous iliac crest bone graft to promote spine fusion. Selecting a specific bone graft substitute can be daunting for the surgeon. In a current single-blind random assigned clinical trial study, we examined instrumented posterolateral fusion with OsvehOss bone grafts (OBG, Osveh Asia, Iran) versus MBCP bone grafts (Biomatlante, France) bone grafts (MBG) in a prospective randomized study. In this research, 19 patients diagnosed with L4-L5 degenerated spondylolisthesis underwent instrumented posterolateral fusion with an OBG (left) and MBG (right). Radiologic fusion and clinical outcomes were investigated. Based on Brantigan-Steffee bone fusion classification system scores, the results show no significant differences between OBG and MBG groups. Pearson correlation coefficient shows a positive correlation between OBG and MBG groups in fusion scores. No complications were observed in the OBG and MBG group postoperatively. The present study showed promising results regarding the efficacy of OsvehOss synthetic bone grafts with successful fusion and clinical scores to those of similar structure synthetic bone grafts.
کلیدواژه‌ها

موضوعات


عنوان مقاله English

Radiographic and Clinical Outcomes of OsvehOss Synthetic Bone Grafts in Spinal Degenerative Diseases, 12-Months Follow-up

نویسندگان English

Heidar Khadivi Ayask 1
Nasrin Sasani 2
Ahmad Safaie Yazdi 3
Farhad Motlagh Pirooz 4
Masoud Golestanipour 5
Ahmad Moloodi 6
Ali Hooshiar Ahmadi 7
Vahideh Sadat Ebrahimi 1
1 Osveh Asia Medical Instrument Co., Mashhad, Iran.
2 Osveh Asia Medical Instrument Co., Mashhad, Iran Mashhad, Iran
3 Department of Neurosurgery, Farabi Hospital, Mashhad, Iran. Mashhad, Iran
4 Department of Neurosurgery, Farabi Hospital, Mashhad, Iran Mashhad, Iran
5 Materials Research Group, Academic Center for Education, Culture & Research (ACECR), Mashhad branch, Azadi square, Mashhad, Iran.
6 Materials Research Group, Academic Center for Education, Culture & Research (ACECR), Mashhad branch, Mashhad, Iran.
7 Faculty Member of Mashhad Branch of Islamic Azad University
چکیده English

The emergence of synthetic bone graft substitutes as a viable option for treatment of a range of bony defects has revolutionized the field of tissue engineering. The iliac crest bone grafting (ICBG) technique for lumbar posterolateral fusion surgery is widely used; however, donor site problems such as pain and sensory disturbance have been reported. Local bone is available for fusion surgery, but its reliability as a graft has not been fully reported. In addition, there has been a focus on finding suitable substitutes for autogenous iliac crest bone graft to promote spine fusion. The selection of a specific bone graft substitute can be a daunting task for the surgeon. In current single blind random assined clinical trial study, we examined instrumented posterolateral fusion with OsvehOss bone grafts (OBG, Osveh Asia, Iran) versus MBCP (Biomatlante, France) bone grafts (MBG) in a prospective randomized study. In this research, 19 patients diagnosed with L4-L5 degenerated spondylolisthesis underwent instrumented posterolateral fusion with an OBG (left) and MBG (right). Radiologic fusion and clinical outcome were investigated. Based on Brantigan-Steffee bone fusion classification system scores, the results show no significant differences between OBG and MBG group. Pearson correlation coefficient shows that there is positive correlation between OBG and MBG group in fusion scores. No complications were observed in the OBG and MBG group postoperatively. The present study showed promising result regarding the efficacy of OsvehOss synthetic bone grafts with the successful fusion and clinical scores to those of similar structure synthetic bone graft.

کلیدواژه‌ها English

OsvehOss
Synthetic bone grafts
Spine fusion
Radiologic fusion

  • تاریخ دریافت 07 شهریور 1403
  • تاریخ بازنگری 21 مهر 1403
  • تاریخ پذیرش 10 آبان 1403